abstract |
Disclosed are pyrimidine 5-membered nitrogen heterocyclic derivatives, methods for their preparation, and pharmaceutical uses thereof. Specifically, a pyrimidine 5-membered nitrogen heterocyclic derivative represented by the general formula (II), a preparation method thereof, a composition containing the derivative, and its use as an SHP2 inhibitor, and a medicament for preventing and/or treating a tumor or cancer ( medicament) is disclosed for its use. |