| abstract |
A method for producing a composition comprising (2R,3R,4R,5S)-3,4,5-trihydroxypiperidine-2-carboxylic acid (idoBR1) is described, said method comprising: (a) cucurbitaceae providing plant material from a plant source comprising plants of the lineage; (b) fractionating the plant material to produce an extract rich in idoBR1; (c) wherein said extract (i) inhibitory activity against sialidase or TNF-alpha; or (ii) assaying for IL-10 stimulatory activity; and (d) formulating the analyzed extract for cosmetics, nutraceuticals, or pharmaceutically acceptable excipients or carriers to produce a cosmetic, nutraceutical or pharmaceutical composition. |