| abstract |
The present invention provides a method comprising the steps of (A) filling a first open cavity formed by a first punch and die with a starting material present in solid form to obtain a second open cavity at least partially filled with the starting material, (B ) closing the second open cavity with a second punch to obtain a first closed cavity, (C) compressing the starting material by moving at least one of the first punch and the second punch at a compression temperature of less than 37° C. obtaining a second closed cavity having a smaller volume than the first closed cavity, thereby resulting in the formation of trapped tablets of the starting material in the second closed cavity, (D) removing the trapped tablets to remove A process for preparing a tablet, comprising the step of immediately after obtaining a tablet having a tablet temperature of less than 37°C, wherein the starting material is a solid at 37°C and 101.32 KPa, (i) a first selected from the list of members 60-100 wt.% of a polymeric stabilizer, (ii) 0-40 wt.% of a second polymeric stabilizer that is Zn-, Ca- or Mg-stearate, (iii) an agent that is zinc oxide, hydrotalcite or sodium benzoate 3 polymer stabilizer 0 to 34 wt. %, (iv) 0 to 20 wt. % of additional components different from the first polymer stabilizer, the second polymer stabilizer and the third polymer stabilizer, wherein the component wherein the sum of (i), (ii), (iii) and (iv) is 100 wt.%, wherein the tablet has a weight greater than 20 mg and less than 330 mg and a cross-sectional dimension greater than 3 mm and less than 18 mm. It relates to a method for manufacturing a tablet. Furthermore, disclosed is a method for stabilizing a polymer that is a polyolefin, polystyrene or mixture thereof, comprising subjecting a tablet to the polymer. Tablets are useful for the dust-free handling of their constituents in the manufacture of stabilized polymers. |