| abstract |
A plug-shaped non-biodegradable implant for replacement and regeneration of living tissue, comprising a base section (2) configured to be fixed to bone tissue, replacing cartilage tissue in the middle region and deep region of the cartilage layer, and configured to have a thickness of at least 0.2 mm a middle section (3), and an upper section (4) configured to grow cartilage tissue up and in to regenerate a superficial zone of the cartilage layer, wherein the middle section and the upper section are porous in the upper section and comprising the same thermoplastic elastomeric material that is non-porous in the middle section, the thermoplastic elastomeric material comprising a linear block copolymer comprising a urethane group and a urea group, substantially free of added peptide compounds having cartilage regeneration properties, the base section material comprising: A biocompatible tissue in the shape of a plug, comprising one of a biocompatible metal such as titanium or a titanium alloy, a ceramic such as sintered crystalline hydroxylapatite, a mineral such as a phosphate mineral, and a polymer, optionally a hydrogel polymer, and combinations thereof. Non-biodegradable implants for replacement and regeneration. |