| abstract |
A binding protein is provided comprising a pseudoFab domain comprising a second VH/VL forming a first functional antigen binding domain and a stabilized knockout domain. Multispecific binding proteins comprising at least one pseudoFab are also provided. Also provided are multispecific binding proteins, binding proteins and nucleic acids encoding the multispecific binding proteins, expression vectors, host cells, pharmaceutical compositions, and therapeutic methods of administering the binding proteins or multispecific binding proteins described herein. |