http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220012117-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e7566f00a7dc09b35e4868c20ad2307 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-90 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-90 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
filingDate | 2020-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab258eeaabe6c37984aa72839ae191d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bd62d13e8de722f65d9feb0a4366c7f |
publicationDate | 2022-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20220012117-A |
titleOfInvention | Developed sleeping beauty transposon system and method of gene transposition using thereof |
abstract | In the present invention, the conventional SB transposon system was applied to CHO cells, and it was confirmed that the protein expression level was higher than that of a general vector. In addition to the existing SB transposon vector ITRs, it was modified by adding an additional pair of ITRs, and a new vector was created. The new vector showed better protein expression than the existing SB transposon, and showed better stability. In addition, an increase in protein expression was confirmed when DNA methylation was inhibited in CHO cells to which the SB transposon system was applied. |
priorityDate | 2020-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 240.