http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220011846-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_050fc7b82c5d17d9aeb63a7cdcc546b3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aceb0794e1c2581bfba4fe7e96a74b3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_332c6a0ad44f03550645396e5c10b031 |
| publicationDate | 2022-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20220011846-A |
| titleOfInvention | A composition and method for preventing or treating neurodegenerative diseases, comprising a substance that increases NIX protein expression |
| abstract | The present invention relates to a composition for the prevention or treatment of neurodegenerative diseases. In the present invention, it was confirmed that NIX-dependent mitophagy was reduced by glucocorticoids, resulting in synaptic dysfunction and cognitive impairment, and glucocorticoids GR-PGC1α -The mechanism of reducing the NIX protein through the NIX axis was specifically identified. Therefore, the conversion of mitochondria damaged by stress into mitophagosomes is inhibited and the pathogenesis of neurodegenerative diseases caused by not being properly arranged at the synapses and terminals of nerve cells. We can suggest a treatment method that restores the function of |
| priorityDate | 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 243.