http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220005045-A

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filingDate 2020-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e745a2e80edc631ad17d74180ce2d80a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcf5ef8099858c766bd47ae3d3ca82b1
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publicationDate 2022-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20220005045-A
titleOfInvention PD-L1 antisense oligonucleotides for use in tumor therapy
abstract The present invention is an oligonucleotide consisting of 10 to 20 nucleotides that hybridizes with SEQ ID NO: 1 encoding PD-L1, wherein the number of potential off-target binding sites is fundamentally reduced, thereby greatly reducing the risk of off-target effects. It relates to oligonucleotides. The present invention also relates to a pharmaceutical composition comprising such an oligonucleotide and a pharmaceutically acceptable excipient.
priorityDate 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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