| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b4be2300a741a69aa1b8bb47a88899f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate |
2020-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f99ec5e724d75e6e6b8be5cd2c7df54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27f9a097b7129109f35f029089c2ea50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d988c0dcdf7154820520553815f4471
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c875c1642409f2ac17f55a16e69db7ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63b2bc59cc830a3361e9a04d1520e5fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42b16244fc101a0af7c9eb5ae50e30a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f520ee53b9fc1bd1acd241db7bf5a9ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d50eb8900e6f6c8609c4f1e62f0b0a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea5679a75f399ac43ab86a1d51a52b69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f0f9eff3e9c02d9185d56ab66a9b984
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d880bda42814e3c81ec4ea46efcb0ce2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_015f184ac56318d8bdf787861e1c3d52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3be81ff1493c1f27af06f401dc5febf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9159947fbc16c3a3a6590cd1a6edb7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efe2f9989426f27a057989f9e3e933c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e843cf5b682aa811ebfa4f8942298a7 |
| publicationDate |
2021-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20210158516-A |
| titleOfInvention |
A pharmaceutical composition containing cell-transducing CRYM fusion protein for preventing or treating motor neuronal disorder |
| abstract |
Challenge: To provide a drug for the treatment of neurological diseases with few or no side effects and excellent efficacy. Solution: The present invention relates to a pharmaceutical composition for the treatment of neurological diseases comprising a cell-permeable CRYM fusion protein, wherein the CRYM fusion protein permeated into the cell increased the cell viability against hydrogen peroxide toxicity, and the level of intracellular reactive oxygen species and hydrogen peroxide reduced DNA fragmentation induced by These results suggest that the CRYM fusion protein has a protective effect against apoptosis and has a therapeutic effect to protect nerve cells from damage to neurological diseases. |
| priorityDate |
2020-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |