http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210141537-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N23-2251 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01086 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N23-2251 |
| filingDate | 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210141537-A |
| titleOfInvention | Fatty acid synthase, inhibitors and modifications thereof and uses thereof. |
| abstract | In a first aspect, the present invention relates to a novel recombinant polypeptide derived from a newly identified gamma subunit of a fatty acid synthase protein complex. In addition, fatty acid synthase protein complexes comprising this novel recombinant polypeptide are disclosed and nucleic acid molecules encoding the polypeptide are also disclosed. Also described are host cells containing a nucleic acid molecule encoding a polypeptide according to the present invention or expressing a polypeptide according to the present invention. Also disclosed is an isolated fatty acid synthase protein complex containing the newly identified gamma subunit. Also disclosed are methods for determining the suitability of candidate compounds capable of inhibiting ketoreductase, enoylreductase or malonyl/palmitoyl transferase present in the FAS protein complex and methods for designing inhibitors of these enzymes. do. Finally, the present invention relates to inhibitors and their use in medical applications. |
| priorityDate | 2019-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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