abstract |
Diagnosis, prevention and provision of therapeutic agents for myeloproliferative tumors. (a) a polypeptide chain consisting of the amino acid sequence shown in SEQ ID NO: 1, or (b) a polypeptide chain consisting of an amino acid sequence in which one or several amino acids are deleted, substituted or added in SEQ ID NO: 1 after cleavage having an antigen recognition site An antibody or functional fragment thereof that binds to a mutant CALR protein, and a drug for diagnosis, prevention and treatment of myeloproliferative tumors containing the antibody. |