http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210133567-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 |
| filingDate | 2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210133567-A |
| titleOfInvention | Method for preparing oral pharmaceutical composition comprising liraglutide and oral pharmaceutical composition manufactured by the method |
| abstract | The present invention relates to a method for preparing an oral pharmaceutical composition containing liraglutide, and more particularly, to an oral pharmaceutical composition comprising the step of preparing an ionic binding complex by mixing liraglutide, anionic bile acid and cationic bile acid derivatives. It relates to a method for preparing a pharmaceutical composition for use. According to the present invention, when an anionic bile acid and a cationic bile acid derivative capable of increasing drug absorption by specifically and selectively binding to a bile acid transporter are mixed with liraglutide to prepare an ionic complex, Absorption efficiency can be increased, and when a buffer is used to prepare an ionic binding complex by binding anionic bile acids and cationic bile acid derivatives to liraglutide, there is a difference between negatively charged anionic bile acids and positively charged cationic bile acids. By inhibiting ionic bonding, an ionic bonding complex having a stable structure can be prepared. |
| priorityDate | 2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.