| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59a31fa4c10a87752fbeae85ebfeae0a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4746
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-19012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2020-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5347af00d7134c85fe932e187ec9b524 |
| publicationDate |
2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20210130195-A |
| titleOfInvention |
Survival-targeted chimeric (SURTAC) molecules |
| abstract |
The present invention provides methods for use to separate ubiquitin molecules from survival-targeting chimeric (SURTAC) molecules and ubiquitinated proteins. In one embodiment, the SURTAC molecule comprises a first binding domain, a second binding domain and a linker domain, wherein the first binding domain is configured to bind a ubiquitinated protein; the second binding domain is configured to bind to a ubiquitin protease that cleaves one or more ubiquitins from the ubiquitinated protein bound to the first binding domain; The linker domain is configured to link the first binding domain to the second binding domain. |
| priorityDate |
2019-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |