| abstract |
Disclosed is a compound of formula (I) or a stereoisomer, tautomer, or salt or solvate thereof: All variables herein are defined herein. These compounds, for example, modulate the activity of the farnesoid X receptor (FXR) as agonists. Also disclosed are pharmaceutical compositions comprising these compounds and methods of using the compounds and pharmaceutical compositions to treat diseases, disorders or conditions associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis and inflammatory disorders. . |