| abstract |
Small molecule potentiators for potassium channels (such as Kv7 potentiators, also referred to as KCNQ potentiators), compositions comprising such compounds, and amyotrophic lateral sclerosis, including amyotrophic lateral sclerosis, and primary lateral sclerosis, pseudomedullary paralysis, progressive medulla oblongata, progressive muscle atrophy and epilepsy. Methods of use of such compounds for the treatment of other neurological disorders caused by, but not limited to, alterations in motor neuron excitability. |