http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210120559-A

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filingDate 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20210120559-A
titleOfInvention Method for screening the skin whitening materials
abstract The present disclosure includes the steps of (a) treating a test substance in cells expressing TPC2 and mCherry-GFP proteins; (b) confirming the fluorescence of the cells treated with the test substance in step (a); and (c) determining the test substance as a skin lightening substance according to the fluorescence displayed in the cells treated with the test substance of step (b). The screening method can confirm whether any material is a skin whitening material by confirming the autophagy activity of melanosomes.
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