Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52fdd060e5959ee1b1aaef321bf0232a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48724e8cdf999d7380ca5424ceafccdf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1617 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 |
filingDate |
2020-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39e17306855d2b0f5cb01225cb958893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a5f12f42ed49e5658a7ab3a8ced940f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b223afa734961e875d3e30521d08923a |
publicationDate |
2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20210114971-A |
titleOfInvention |
Liposome composition comprising liposomal prodrug of mitomycin C and preparation method |
abstract |
A liposome composition comprising a lipophilic prodrug of mitomycin C with an improved pharmacokinetic profile is described. Methods for preparing compositions using a solvent system consisting of ethanol and tertiary butanol mixed in appropriate ratios are also described. In an embodiment, the liposome composition is a population of lipid nanoparticles and a pharmaceutically acceptable vehicle, wherein the population of lipid nanoparticles consists of a first fraction of spherical liposomes and a second fraction of rod-shaped lipid nanoparticles, and , wherein the second fraction is less than about 15% of the population of lipid nanoparticles. |
priorityDate |
2019-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |