http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210100848-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a4985a638362ed12762bacae2088b21 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-531 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
filingDate | 2020-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80c661a5846a37c8eab4aaa1425cc5c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_720f0fe2d0d7234eaebaadd52378c959 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91e0c08b4c06e71beb15abf7ca1486c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ee6ac68ad8d644b4dc6e7730e0706aa |
publicationDate | 2021-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20210100848-A |
titleOfInvention | Method for manufacturing nanoparticles having hydrophilic ligands and antibodies conjugated to each surface of them, nanoparticles manufactured using same method, complex containing same nanoparticles, and diagnostic kit containing same nanoparticles |
abstract | The present invention relates to a method for producing nanoparticles in which a hydrophilic ligand and an antibody are conjugated to a surface, comprising the steps of preparing nanoparticles having a hydrophilic ligand bound to the surface, diluting the nanoparticles in a buffer to form a nanoparticle mixed buffer Step, mixing the antibody with the nanoparticle mixing buffer and stirring to form a nanoparticle-antibody conjugate mixed buffer, and adding a blocking solution to the nanoparticle-antibody conjugate mixed buffer and stirring to mix the blocked nanoparticles-antibody conjugate By including the step of forming a buffer, direct conjugation of the antibody is possible without the need for a separate chemical linker, thereby improving the efficiency and reproducibility of the production process. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022177041-A1 |
priorityDate | 2020-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.