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publicationDate 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20210095796-A
titleOfInvention sensing systems
abstract The sensing system includes a charge sensor, the charge sensor including two electrodes and an electrically conductive channel connecting the two electrodes. The sensing system also includes a charged molecule attached to an electrically conductive channel. The charged molecule comprises a recognition site for reversibly binding to a label of a labeled nucleotide; have an unbound sympathetic conformation associated with an unbound charge configuration; And when the recognition site is bound to the label, it has a favorable conformation associated with charge configuration. The charge configuration is different from the unbound charge configuration. The sensing system further comprises a polymerase attached to the electrically conductive channel or to the charged molecule.
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