| abstract |
The present invention relates to a liposome with improved cell permeability and a drug delivery system comprising the same, wherein the liposome has an internal space isolated by a lipid layer membrane, wherein the lipid layer includes a sterol-based compound, a poloxamer, and a bile acid. The release in the blood environment can be controlled, the cell permeability of bendamustine encapsulated in the liposome can be improved, and the efflux action by p-glycoprotein can be inhibited. |