abstract |
The invention features ALK2 antibodies and antigen binding fragments thereof (eg, ALK2 binding fragments). The present invention also provides a method for treating bone disease or injury, low red blood cell levels (eg, anemia or blood loss), ectopic ossification (eg, ectopic ossification resulting from advanced fibrodysplasia) using an ALK2 antibody or antigen-binding fragment thereof. It features pharmaceutical compositions and methods for treating Sjogren's syndrome (eg, dry eye associated with Sjogren's syndrome), multiple osteochondroma, diffuse endogenous glioma, posterior capsule opacity, or cardiac hypertrophy and/or cardiac fibrosis. |