Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe2d8a10ec14cd3998ef9c0637e811b1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa017eaf456dab7ac809c45bff377adb |
publicationDate |
2021-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20210081372-A |
titleOfInvention |
Cleavable CXCR3 activators and methods of use thereof |
abstract |
CXCR3 cleavable activators and methods of use Recombinant CXC motif chemokine ligand (CXCL) peptides modified to introduce cleavage sites for proteases, such as proteases that are activated during inflammation, are described. The CXCL peptide has the ability to activate CXCR3 until cleaved by a protease. Proteolytic cleavage of the CXCL peptide minimizes the pro-inflammatory response and inhibits the development of fibrosis. |
priorityDate |
2018-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |