| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3c4190bc3fdd594ee3a4c53d9d342a0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0697 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0793
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51aa10a8fffba8d34091f5f42232a175
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33383f6f293effada4535e03bce1827f |
| publicationDate |
2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20210078705-A |
| titleOfInvention |
Parkinsons's disease model |
| abstract |
The present invention relates to a medium composition for inducing differentiation of stem cells into midbrain organoids, comprising a SMAD inhibitor and CHIR99021, an agonist of the WNT signaling system, as an active ingredient, and a method for differentiating stem cells into midbrain organoids using the medium composition. As a method, when stem cells are cultured using the medium composition of the present invention, they can be differentiated into homogeneous midbrain cells with high efficiency, and the midbrain organoids prepared by the manufacturing method of the present invention can be used to develop various new drugs and simulate diseases. It can be used as a platform that can be used for research and can also be used in the field of tissue transplantation. |
| priorityDate |
2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |