| abstract |
The present invention provides a combination therapy of a recombinant vaccinia virus (especially an oncolytic vaccinia virus) and another cancer therapy for use in treating cancer, and a pharmaceutical composition and combination kit for use therein. More specifically, therapy by a combination of an immune checkpoint inhibitor with a vaccinia virus comprising a polynucleotide encoding interleukin-7 (IL-7) and a polynucleotide encoding interleukin-12 (IL-12), and Pharmaceutical compositions and combination kits used for this are provided. |