http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210062442-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87b8b0fc9402429603f11cca4b9a107f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-415 |
| filingDate | 2019-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bf5a3be7482590a7ca5899993e66682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fae00a8e4c043fd553aa60ea46421f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12ed82df0a738e5ee8f1c87c19b98fdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c6d0d6795a08d0d3c6ef1980beac3f3 |
| publicationDate | 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210062442-A |
| titleOfInvention | Novel antigenic proteins and their use to detect wheat-dependent exercise-induced anaphylaxis |
| abstract | The present invention relates to an antigenic protein consisting of an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2, wherein the antigenic protein induces wheat-dependent exercise-induced hypersensitivity, which can be used to diagnose wheat-dependent exercise-induced hypersensitivity. I can. Specifically, the antigenic protein was identified as a reactive protein through a two-dimensional immunoblot analysis using Opry flour protein in which omega-5 gliadin was partially deleted and serum of a patient with WDEIA, and also, the central antigen of WEDIA, omega- 5 It was confirmed that it also reacted with a monoclonal antibody against gliadin. As a result of analyzing the antigenic protein by mass spectrometry, it was confirmed that it corresponds to a novel omega-5 gliadin gene encoded on chromosome 1D. Therefore, it was confirmed that the antigenic protein reacted with a monoclonal antibody against omega-5 gliadin, which is the central antigen of WDEIA patient or serum of WDEIA patients, using the antigenic protein that causes wheat-dependent exercise-induced hypersensitivity. Wheat-dependent exercise-induced hypersensitivity can be diagnosed. |
| priorityDate | 2019-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 317.