| abstract |
The present invention relates to a prebiotic composition for use in a method for treating or prophylactic treatment of a disorder related to an abnormal composition or function of an intestinal microbiome in a subject, wherein the use comprises oral administration of a prebiotic composition to a subject. Wherein the composition contains at least 0.1% by weight of a dry substance of RG-I polysaccharide derived from fruit, carrot, pea, chicory or sugar beet, and the RG-I polysaccharide has a molecular weight exceeding 15 kDa, and galactu It has a backbone consisting of a ronic acid residue and a rhamnose residue, and the rhamnose residue is contained in an alpha (1 → 4)-galacturonic-alpha (1 → 2)-rhamnose residue, The molar ratio of lacturonic acid residues to rhamnose residues is in the range of 20:1 to 1:1. |