| abstract |
The present invention relates to compounds or pharmaceutically acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. Pharmaceutical compositions comprising an effective amount of a compound of Formula I, Formula II, Formula III, Formula IV, Formula V or Formula VI and methods of treating ocular and skin disorders include topical eye drops, topical pastes, ocular solutions, device-drug delivery , Oral, oral, rectal, topical, transdermal, transmucosal, lozenges, spray, intravenous, oral solution, nasal spray, oral solution, cream, skin ointment, gel, lotion, suspension, oral spray, Oral mucosa tablets, can be formulated for parenteral administration, syrup or injection. Such compositions can be used for the treatment of skin diseases such as acne, rosacea, and eye diseases such as hyperemia, glaucoma, presbyopia, IOP, cataract, dry eye and oGVHD. |