| abstract |
Isolated binding proteins are provided comprising an antigen binding domain that binds to the NS1 protein, and comprising specific heavy and light chain CDRs. The binding protein can specifically identify and bind NS1, has a relatively high sensitivity and specificity, and detects dengue virus. In addition, the binding protein does not need to be produced by injecting hybridoma cells into the mouse peritoneal cavity, whereas it simplifies production, thereby stabilizing antibody function. |