http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210049026-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33661d593717784c04caa1177ede0bb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6c945f182833bcc8718c1244788bc30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73e1811d43cc130de2daafc08fecf8eb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
| filingDate | 2019-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f08f6682419f5f62a19e0ed94181be9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06f9f9b0ecd1147005c68d31f52efa27 |
| publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210049026-A |
| titleOfInvention | Blood biomarkers in stroke |
| abstract | Stroke is a highly destructive disorder that significantly causes death, disability and health care costs. The current challenge is to prevent apoptosis in the later stages and expand the window of treatment using simultaneous therapy. A potential diagnostic method for diagnosing stroke is the use of RNA in the blood as a biomarker, a new emerging field in medicine. Here, the inventors study gene expression in brain and blood after the onset of cerebral ischemia. Studies of macaque microarray expression data from brain and blood show that ischemic and non-ischemic samples can be differentiated based on their expression profiles, and that the majority of highly differentially expressed genes are upregulated 6 hours post ischemia in the ischemia scenario. It turned out. As a result of comparison of genes differentially expressed in brain and blood, it was found that the gene expression patterns were significantly overlapped. The data indicated that a common signature exists between the ischemic brain and blood, which is used to profiling biopsy transcriptome expression characterizing patients with ischemic stroke to develop companion biomarkers for the evaluation of neuroprotective drugs in patients. Supports the development of blood transcriptomes as tools for |
| priorityDate | 2018-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1209.