| abstract |
The present invention relates to a composition for preventing, improving or treating sleep disorders containing turmeric extract as an active ingredient. The turmeric extract of the present invention provides the effect of reducing elevation time, increasing sleep duration, and increasing non-REM sleep at approximately the same level or improved level as redolmin or diazepam, which are drugs used as conventional sleep inducing agents. In addition, the turmeric extract of the present invention suppresses the sleep effect by the same mechanism that the sleep effect of pyrylamine maleate salt, which is known as a histamine receptor antagonist, is completely inhibited by 2-pyridylethylamine dihydrochloride, a histamine receptor agonist, It acts as a natural antihistamine. In addition, since it is derived from a natural product, turmeric, there is no side effect of forming cognitive impairment, tolerance or dependence even when used for a long time. Therefore, the composition for preventing, improving or treating sleep disorders comprising the turmeric extract of the present invention as an active ingredient is very useful in the manufacture of competitive food compositions and pharmaceutical compositions. |