| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8aa76a714f4f64598f2ad4649a9eb3af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0312
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0339 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
| filingDate |
2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ec21bbdc0424848311e11e851e2665e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_277a723cffc19485d0b4100675846628
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c5985e538b6864a64bdc73d486de31c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaf78073af86b40e9ec0009474cc1fd5 |
| publicationDate |
2021-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20210035917-A |
| titleOfInvention |
Method for screening drug and therapeutic target used for treating alzheimer's disease |
| abstract |
The content described herein is by inhibiting and down-regulating the amount of PI4KIIIα protein, RBO/EFR3/EFR3A/EFR3B membrane protein, TTC7 protein, and the membrane protein complex formed by the protein or related enzyme activity that promotes Aβ secretion by neuronal cells. It is the use of genetic means or related inhibitors to reduce AD model Drosophila and mouse neuronal dysfunction by reducing Aβ accumulation in neurons. |
| priorityDate |
2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |