| abstract |
The present invention is a multilayered suppository formulation comprising an outer layer comprising a first pharmacological component and an inner layer comprising a second pharmacological component, and a composition for preventing or treating colon cancer comprising the same It is about. The present invention reproduces the sequence of release and the release interval of a combination drug sequentially administered in combination, for example, FOLFOX. Accordingly, the present invention can be usefully used as an efficient formulation that concentrates pharmacological effects, reduces side effects, and greatly improves patient medication convenience by locally acting on a complex drug administered systemically through intravenous injection. . |