http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210030805-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3164a963ca21cec1151213cb1bb95e77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9305fc720f87097494d965f1b1310e24 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
| filingDate | 2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fe8d41fb5cebae0dba350b678a4300c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f79384f705bedae8ba6a0cfbcf1ec879 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ba706eeb1d63031d035d4347b58faf8 |
| publicationDate | 2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210030805-A |
| titleOfInvention | Composition for enhancing gene editing efficiency by homologous recombination comprising autophagy inducing agent |
| abstract | The present invention relates to a composition for increasing gene editing efficiency by homologous recombination comprising an autophage inducing agent and a method for increasing gene editing efficiency. The technology according to the present invention can significantly increase the efficiency of homologous recombination gene editing by, for example, CRISPR gene scissors, by inducing autophagy in human cells and animal cells, up to about 10 times, and also enhance the intrinsic autophagy mechanism of cells. By using it, the range that can be applied is wide, and it can be particularly applied to in vivo , thereby overcoming the limitations of the existing homologous recombination efficiency enhancement technology. Furthermore, the technology of the present invention is expected to be useful in various fields such as life science research, gene therapy, and new drug development by enabling accurate and efficient gene correction. |
| priorityDate | 2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.