| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a8429b6c408095fb5624d842213c2f4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-526
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2318-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate |
2019-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7419de499170cdce111f4fc05c829c85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b581a684aae28094f73dff867a5af0f4 |
| publicationDate |
2021-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20210028155-A |
| titleOfInvention |
CH3 domain epitope tag |
| abstract |
The present invention relates to the incorporation of one or more non-homologous antibody epitopes into the AB, EF or CD structural loops of the constant heavy chain domain 3 (“CH3 domain”) of an engineered antibody or Fc-linked therapeutic agent. A non-homologous epitope acts as a “epitope tag” that is specifically detectable by an epitope tag-specific detector antibody, regardless of the tag specificity of the tagged substance. Thus, epitope tags are useful for rapid detection of any tagged antibody or Fc linking agent in biological samples, including samples that also contain endogenous antibodies. |
| priorityDate |
2018-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |