| abstract |
The present invention relates to a composition comprising a pyrimidinecarboxamide derivative as an active ingredient, and more specifically, a pyrimidinecarboxamide derivative, a pharmaceutically acceptable salt thereof, as an active ingredient, PIM serine/threonine kinase enzyme It relates to a composition for preventing, ameliorating or treating diseases associated with excessive activity. Pyridinecarboxamide derivatives according to the present invention can inhibit or inhibit the activity of PIM serine/threonine kinase enzymes, and thus are used as pharmaceutical compositions that can fundamentally prevent or treat diseases related to excessive activation of PIM serine/threonine kinase enzymes. In addition, it can be used for the development of a biological agent for the treatment of diseases related to excessive activity of the PIM serine/threonine kinase enzyme, and for various studies on the expression or inhibition of the activity of the PIM serine/threonine kinase enzyme. |