| abstract |
The present invention provides monoclonal antibodies that bind to Factor XII (FXII) protein, and methods of use thereof. In various embodiments of the invention, the antibody is a fully human antibody that binds to FXII and the activated form of FXII (FXIIa). In some embodiments, the antibodies of the invention are useful for inhibiting or neutralizing FXII activity, thus providing a means of treating or preventing diseases, disorders or conditions associated with thrombosis in humans. |