| abstract |
The present invention provides a compound for use in treating cancer cachexia in a subject, wherein the compound is a compound of formula I or a pharmaceutically acceptable salt or solvate thereof: In Formula I, -R 1 represents a C 1 -C 6 alkyl group, the alkyl group carries 5 or less -OR 2 substituents, R 2 represents hydrogen, or C 1 -C 6 alkyl, or -OR 2 represents (R) Represents a -3-hydroxybutyrate moiety; or -R 1 is a moiety derived from the alcohol HOR 1 , and the alcohol is a sugar. Typically, the invention also provides treatment of conditions associated with cachexia, such as muscle wasting. |