| abstract |
A method of inducing conjunctival epithelial cells, conjunctival goblet cells and conjunctival epithelial stem/progenitor cells, characterized in that the colony of pluripotent stem cells is cultured in a medium containing an EGF (Epidermal Growth Factor) signal transduction activating factor to induce differentiation. According to the present invention, conjunctival epithelial cells, conjunctival goblet cells, conjunctival epithelial stem/progenitor cells can be derived from pluripotent stem cells including iPS cells, so basic studies of conjunctival epithelial cells and conjunctival goblet cells, refractory ocular surface disease It is extremely useful for regenerative therapy or research related to the disease. |