| abstract |
The present invention relates to vaccine compositions, in particular to vaccine compositions having a large antigenic component, for example greater than 50 kDa, or multimer, ie comprising subunits. These antigenic components are of particular importance because they can represent antigenic components from pathogens that are currently not vaccinated. The present invention relates to a composition comprising particles representing an antigenic component, wherein the composition comprises an antigenic component comprising a first peptide tag and a moiety comprising a second peptide tag, wherein the antigenic component and moiety T is linked via isopeptide bonds between the first and second peptide tags, the antigenic component exceeding 50 kDa, or alternatively multimer. |