http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210010366-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e078e4e4626c5c52bf207640881d8eaf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate | 2020-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bec47b7227237c3ea13a2132902efbc5 |
| publicationDate | 2021-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210010366-A |
| titleOfInvention | Fusion tag for preparing glucagon-like peptide-1 or analogues |
| abstract | An embodiment of the present invention relates to a fusion tag, a fusion polypeptide comprising the fusion tag and glucagon-like peptide-1 or an analog thereof. If the novel fusion tag according to the present invention is used, the yield of glucagon-like peptide-1 or an analog thereof can be improved compared to the conventional fusion tag. In particular, it is useful when a glucagon-like peptide-1 or an analog thereof having a relatively small molecular weight and an amino terminus that is easily degraded is prepared using genetic recombination technology. In addition, the fusion polypeptide containing the fusion tag according to an embodiment of the present invention is protected from proteolytic enzymes of the host cell by inducing expression in the host cell in the form of an inclusion body, thereby stably glucagon-like peptide-1 or its It has the advantage of being able to produce analogues. Therefore, it is possible to provide a method for producing a recombinant glucagon-like peptide-1 or an analog thereof having improved stability and yield compared to the case of using a conventional fusion tag. |
| priorityDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 626.