| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff283c7d6797987f01db547f606e6b32 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-364 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f98f1cbae8f905b4f00983fc406776e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96ba575f0ddc5027de66d94a7ba6442a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d8c618b436f4777e1fb776da152ed22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cd2fa61524dc12d33d4c3f0c3954439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b330953c6c60745e68a75b5fbb45f7aa |
| publicationDate |
2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20210006692-A |
| titleOfInvention |
Screening method of therapeutic agent for decidualization-related disease |
| abstract |
The present invention relates to a method for screening a therapeutic agent for a condition related to decidualization occurring in a microgravity environment, and the expression of FOXO3a protein and the degree of autophagy activation of endometrial stromal cells (hESCs) in a virtual microgravity environment are reduced, and thereby the uterus It was confirmed that the endoplasmic reticulum decreased cell stromal cells and migration, and consequently inhibited decidualization. Therefore, confirmation of the expression level of FOXO3a and confirmation of whether the degree of autophagy activation is reduced can be usefully used in screening for therapeutic candidates for decidualization-related conditions. |
| priorityDate |
2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |