| abstract |
The present invention is an injection-type hydrogel capable of providing a crosslinking point and physiological activity of a hydrogel using a green tea extract and epigallocatechin gallate (EGCG) capable of removing radicals in the body, and a method for preparing the same. It is about application. In the present invention, the EGCG duplex was introduced into the hydrogel in order to impart rapid crosslinking of the hydrogel and the ability to modulate the immune response. In addition, EGCG, which is known as a competitive inhibitor of tyrosinase, is reactivity with tyrosine and tyrosinase is significantly higher than that of tyrosine and tyrosinase, so that tyrosinase derived from Streptomyces avermitilis is used. Used as a crosslinking agent. The present invention has developed a hydrogel system that can be used as a crosslinking point by introducing an EGCG molecule into a hydrogel, can impart tissue adhesion, and can also regulate an immune response in the body. |