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filingDate 2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_448dd44a985e5b7f8ff4ee22c97049cc
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publicationDate 2020-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20200145981-A
titleOfInvention Method for improvement of glutaric acid production by applying dual vector system and modulating cofactor specificity of lysin biosynthesis enzyme in recombinant Corynebacterium glutamicum strain
abstract The present invention is 5-aminovalerate aminotransferase (DavT), glutarate semialdehyde dehydrogenase (DavD), lysine 2-monooxygenase (lysine 2-monooxygenase) ; DavB), delta-aminovaleramidase (DavA), and dihydrodipicolinate reductase (DapB) derived from E. coli. Including the step of culturing the recombinant Corynebacterium glutamicum strain for producing glutaric acid and the recombinant Corynebacterium glutamicum strain transformed with a second vector containing a first vector and a pBL1 replication origin. It relates to a method for producing glutaric acid. The present invention relates to a method of increasing the production of glutaric acid through a dual vector system by identifying the problems of the existing recombinant Corynebacterium glutamicum strain for producing glutaric acid. In the case of producing glutaric acid using the recombinant Corynebacterium glutamicum strain, it is possible to selectively produce glutaric acid without by-products as well as excellent production.
priorityDate 2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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