http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200143391-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d33087dfb06f23a561b692aecc073feb |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7125 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate | 2019-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f445509bfed0080d02b6a5fe640025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5927d3d5e82f2bead26e2a3e679e7d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57e0ba2ae1dfde0d04859954f36e506e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_971f166af1c028353d6a1b09dcb81f75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8f575b4520bbef3be1530a861c77187 |
publicationDate | 2020-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20200143391-A |
titleOfInvention | 5'-cap-trinucleotide- or higher order oligonucleotide compounds and their use in RNA stabilization, protein expression and therapy |
abstract | The present invention relates to the stabilization of RNA by 5'-cap compounds, in particular such 5'-cap compounds, and compositions and cells, such as pharmaceutical compositions comprising RNA modified with such 5'-cap compounds, as well as the present invention. A method for producing a peptide or protein of interest using the composition or cell according to the invention is provided. Furthermore, the present invention relates to RNA, compositions, or cells for use in therapy, in particular for use in methods of treating diseases or disorders by protein replacement therapy, genetic engineering, genetic reprogramming, and immunotherapy; Methods for increasing the stability of RNA in cells; Methods for increasing the expression of RNA in cells; And a method for providing an RNA having a 5'-cap structure. |
priorityDate | 2018-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1138.