| abstract |
The present invention relates to a composition for preventing, improving or treating metabolic syndrome, comprising a complex of Indian gooseberry (Amra) extract and sprout barley extract as an active ingredient. Specifically, the complex of Indian goose berry extract and sprout barley extract according to the present invention inhibits the enzymatic activity of pancreatic lipase than each single substance, inhibits digestion and absorption of ingested fat, and promotes GLUT4 signaling including IRS and PI3K. By controlling the absorption of blood sugar and inhibiting the synthesis of fat from sugar metabolism, and promoting fat decomposition through the regulation of cAMP expression, it suppresses fat accumulation by increasing the amount of glycerol discharged out of cells, and reduces body weight, blood sugar, blood insulin, and blood glycated hemoglobin. Since it shows a synergistic effect in improving obesity or diabetes, it can be used as a pharmaceutical composition or health functional food for the prevention or treatment of metabolic syndromes such as obesity and diabetes. |