| abstract |
The present invention relates to the formulation of at least one digestive enzyme, such formulation: -From 50 μm to 1200 μm in size, -Strictly hydrophobic, -Containing solid lipid particles that do not contain water, organic solvents, surfactant compounds and polymers: -At least one digestive enzyme, -Contains a strictly hydrophobic, non-hygroscopic waxy matrix, Wherein the at least one digestive enzyme is: -Have a homogeneous distribution in each solid lipid particle of the formulation, -Distributed without a distribution gradient toward the inside of the waxy matrix, -Represents 0.1% to 90% of the mass of the formulation, The formulation has a melting point of 20°C to 65°C. |