| abstract |
The present invention relates to a Cacb1-derived peptide and a variant of the Cacb1-derived peptide, and a composition for preventing or treating hypertension comprising the same, and a composition for relaxing blood vessels. The Cacb1-derived peptide and the variant of the Cacb1-derived peptide of the present invention have excellent blood pressure lowering effect, have few side effects, and are easy to manufacture and industrialize, and thus can be usefully used in the development of a new therapeutic agent for hypertension. In addition, due to its potential vasodilating effect, it is expected to be used as a therapeutic candidate for diseases that can be treated or ameliorated by vasodilation such as angina pectoris, prostatic hyperplasia, and erectile dysfunction. |