| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d4ad61d0af1fd483d31d1c5df9b9b76 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y107-03003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
| filingDate |
2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccefcd1922b28fd46517dc3f62ea5eb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6e2fefe80066cb67f019c906e7b6d5a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93ed20fcefd2c6ba86af06ee9031f9a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61e6835dedcdea4f2bf76ee172f50e61 |
| publicationDate |
2020-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20200132740-A |
| titleOfInvention |
Composition for preventing or treating Gout comprising stem cells overexpressing Uricase |
| abstract |
The present invention relates to a composition for the prevention or treatment of gout comprising stem cells overexpressing urate enzyme as an active ingredient, and is transformed with a minicircle vector comprising a gene encoding a uric acid enzyme protein according to the present invention. Mesenchymal stem cells not only confirmed that uric acidase was overexpressed in vitro, but also when urate-expressing mesenchymal stem cells were administered to a mouse model administered with a high concentration of uric acid crystals, it was confirmed that they effectively inhibited inflammation. It can be usefully used as a composition for preventing or treating acute gout or chronic nodular gout. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20230030889-A |
| priorityDate |
2019-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |