| abstract |
The present invention relates to an immunoglobulin heavy chain variable region (V H ), an immunoglobulin light chain variable region (V L ), an immunoglobulin light chain constant region (C L ), an immunoglobulin heavy chain constant region (C H ), and a peptide linker (PL1 and PL2). ), and their use for therapeutic or diagnostic purposes, wherein V H is fused to V L through PL1 and C L is fused to C H through PL2. The present invention also relates to a recombinant nucleic acid molecule encoding the antibody, an expression cassette, a vector, a viral particle, a host cell, a transduced organism or a pharmaceutical composition comprising the recombinant nucleic acid molecule. |