http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200128850-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87b8b0fc9402429603f11cca4b9a107f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7034 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 |
| filingDate | 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f235adce674dad74f59c43f73aeafda9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19fd9458de97b9e757dbca73a74ac3a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0212040368c660c61796ff5812154ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18779386f357e28afe24ea3281bbe223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8097c0bdbb9c546822190af88712e2b9 |
| publicationDate | 2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20200128850-A |
| titleOfInvention | Pharmaceutical composition for preventing and treating prostate disease, comprising the compound isolated from Platycodon grandiflorum and Platycodon grandiflorum extract as an active ingredient |
| abstract | The present invention relates to a pharmaceutical composition for prostate disease prevention and treatment comprising a bellflower ( Platycodon grandiflorum ) extract, a fraction, and a method of obtaining an isolated active compound thereof, and an extract, fraction or an isolated active compound thereof prepared therefrom, In the present invention, it was confirmed that (1) hot water, 30% alcohol, and 100% alcohol extract of bellflower did not have cytotoxicity against human prostate stromal cells (WPMY-1) and human prostate cancer cell lines (LNCap, PC-3), (2) It was confirmed that the 30% alcoholic extract of bellflower (1) above inhibited prostate cancer cell proliferation in a human prostate cancer cell line (LNCap). (3) Therefore, it was confirmed that a normal-butanol fraction was obtained using 30% alcohol extract, and the human prostate cancer cell line (LNCap) inhibited prostate cancer cell proliferation. In addition, (4) treatment of the effective compound isolated from bellflower to human prostate cancer cell line (LNCap, PC-3) to inhibit prostate cancer cell proliferation, thereby preventing prostate disease prevention and treatment pharmaceutical composition or prostate disease prevention And it can be used as a health functional food composition for improvement. |
| priorityDate | 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.